UPHA Pharmaceuticals Manufacturing Sdn Bhd was established in 1976 in Bangi, Selangor. It was acquired by CCM Berhad in 1995 and became a wholly-owned subsidiary. In 2015, UPHA went through a merger exercise with the consolidation of all pharmaceutical companies under CCM Duopharma Biotech Berhad before the eventual de-merger between CCMD and CCM Berhad in 2017.
UPHA manufactures a wide range of Ethical and OTC products, mainly in Oral Solid Dose (OSD), liquids and cream forms. It has a state-of-the-art Intermediate Bulk Container (IBC) manufacturing format which is capable of manufacturing 1-ton batches to produce tablets, capsules and mini-tablets in capsules.